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Cancer Therapy

Updated phase II lung cancer clinical trial results presented at ASCO

Published in Cancer Weekly, July 6th, 2004

Genaera Corp. (GENR) announced updated interim safety and efficacy results for its antiangiogenic drug, squalamine, in its phase IIb non-small cell lung cancer (NSCLC) clinical trial.

The presentation was made at the 40th annual meeting of the American Society of Clinical Oncology (ASCO), held in New Orleans, Louisiana.

This multicenter, randomized study enrolled 45 stage IIIb or stage IV advanced lung cancer patients who were to receive weekly dosing of squalamine, combined with weekly chemotherapy of carboplatin and paclitaxel. All 45 patients were evaluated for safety. Overall, the combined drug regimen was well-tolerated, with fewer serious...

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