Cancer Weekly

Cancer Risk Factor - Exposures to magnetic fields heighten a woman's risk for breast cancer

Diagnostics - Prostate specific antigen ratios offer a better way to detect prostate cancer

Gastroenterology - Intravenous morphine improves MR cholangiopancreatography image quality

Head and Neck Cancer - Autofluorescent endoscopy reveals precancerous conditions in the larynx

Acute Leukemia - Arsenic trioxide can help patients with advanced acute promyelocytic leukemia

Acute Leukemia - Fatal intracranial hemorrhage can occur in acute leukemia patients

Advanced Solid Tumors - Phase I trials initiated for Symadex in advanced solid tumors

Adverse Side Effects - Doctors over-prescribe 5-HT3 antagonists for emesis control to cancer patients

Awards - Cancer cell detection technology wins Kaye award

Awards - Scientist honored for studies of genetic interference with tumor development

Bile Duct Cancer - Serum sFas/sFasL levels have prognostic value in bile duct cancer patients

Biochemistry - Interleukin 6 mediates cross-talk between prostate cancer cells

Bladder Cancer - Epigallocatechin gallate arrests the growth of bladder cancer cells

Bladder Carcinoma - Imaging of the various continent urinary diversions can be difficult

Brain Cancer - Cerebral blood flow indices outline glioma vascularity in xenografts

Brain Cancer - Extracellular matrix heterogeneity is a controlling element of glioma invasion

Brain Cancer - First patient enrolled in TheraCIM hR3 trial for pediatric glioma

Brain Cancer - Protein shift predicts brain cancer grade, recurrence, patient survival

Brain Cancer - Zadaxin plus BCNU show promise as glioblastoma multiforme therapy, study shows

Brain Edema - Aquaporins may hold the key to understanding and treating brain edema

Brain Imaging - Imaging of brain function using SPECT has wide potential

Brain Tumors - In vitro study shows that neomycin inhibits glioma cell migration

Breast Cancer - Abraxane active in taxane-refractory breast cancer patients

Breast Cancer - Alpha 6 integrins contribute to breast carcinoma survival and progression

Breast Cancer - Bookend T₁ measurements on MRI give a better depiction of breast tumors

Breast Cancer - Breast cancer in black women more aggressive than in white women, study shows

Breast Cancer - Cathepsin D decrease in breast cancer mediated by IGF-II receptor

Breast Cancer - CellSearch System launch planned for fall 2004

Breast Cancer - Comprehensive breast cancer book replaces fear with fact

Breast Cancer - Gene's activity level may be early predictor of disease aggressiveness

Breast Cancer - IFI16 required for maximal activation of p53 induced by ionizing radiation

Breast Cancer - Innervated autologous flaps are feasible in breast reconstruction

Breast Cancer - Lifesaving potential of mammograms lost due to underuse

Breast Cancer - New trade names announced for efaproxiral in the U.S., Europe

Breast Cancer - Partial breast radiation procedure may benefit patients

Breast Cancer - Risk of fast-growing breast tumors higher in young black women

Breast Cancer - Utility of sentinel lymph node biopsy in breast cancer reviewed

Breast Cancer - Weekly paclitaxel better than standard dosing schedule for metastatic disease

Breast Cancer - p300/CBP-associated factor is a p53 target in breast tumors

Business Update - UNC HCS inks supply chain agreement

Cancer Clinical Trials - Doctors stumble when seeking informed consent from study participants

Cancer Diagnosis - Digital microscopy enhances accuracy of immunohistochemical scoring

Cancer Epidemiology - Age gap brings cancer inequality

Cancer Facility - Huntsman Cancer Institute opens hospital at the University of Utah

Cancer Metastasis - Tandem BRAF mutations occur early during primary melanoma invasion

Cancer Prevention - 1,25-Dihydroxyvitamin D-3 analogues protect skin cells from ultraviolet B

Cancer Survivors - Victims of childhood cancer return favor to family

Cancer Therapeutics - Report predicts emerging market leaders in solid tumor drug market

Cancer Therapy - Common "signature" found for different cancers

Cancer Therapy - Companies report "compelling data" from phase I prostate cancer study

Cancer Therapy - Company reports broad utility of lead product ADVEXIN

Cancer Therapy - DNA damaged by paclitaxel is repaired over time

Cancer Therapy - Data presented from trials using Xcellerated T Cells in cancer patients

Cancer Therapy - Engineers, physicians work to improve radiation therapy

Cancer Therapy - Full enrollment reached in Virulizin phase III registration clinical trial

Cancer Therapy - IL-21 enhances rituximab-mediated killing of B-lymphoma cell lines, data shows

Cancer Therapy - Individualized medicine may be possible with pharmacogenomics

Cancer Therapy - Labopharm inks first agreement of polymeric nanodelivery systems technology

Cancer Therapy - Milestone achieved for initiation of phase I trial for anticancer compound

Cancer Therapy - Nanoshells cancer treatment proves effective in first animal test

Cancer Therapy - New therapy disguises cancer cells as viruses

Cancer Therapy - Novel cancer compound targets EGFR pathway; demonstrates positive trial results

Cancer Therapy - Oncogenomics is necessary to develop new cancer therapies

Cancer Therapy - Predicting disease may become possible using genomics

Cancer Therapy - Protein can reverse DNA damage

Cancer Therapy - Scottish research yields new clues to improve radiotherapy

Cancer Therapy - Utility of radiofrequency ablation of liver metastases reviewed

Cancer Therapy - Veglin trial shows potential in fighting angiogenesis and tumor progression

Cancer Therapy - Weekly administration of Cloretazine well tolerated in cancer study patients

Cancer Treatment - CuraGen licenses Seattle Genetic technology for $2 million

Cancer Treatment - Merck, Vertex collaborate to develop cancer drug

Cancer Vaccine - Adenovirus encoding HCA661 targets hepatoma cells

Cancer Vaccine - CTLA-4 blockade plus DNA vaccine enhances tumor immunity

Cancer Vaccine - GADD34 up-regulation mediates activity of mitomycin C and herpesvirus

Cancer Vaccine - Gene transfer of OX40 ligand to tumor cells enhances antitumor immunity

Cancer Vaccine - Peptides immunogenic for HLA-A2+ cancer patients identified

Carcinogenesis - TP73 gene alterations may play role in development of cervical carcinoma

Carcinogens - Bcl-2 overexpression supports tetrachlorohydroquinone-related tumor growth

Carcinogens - Organochlorines don't influence breast cancer in women with certain genotypes

Cell Biology - A challenge model portrays tissue kallikrein in tumor-endothelial interactions

Cell Biology - New insight into cancer metastasis

Cervical Cancer - $1.1M grant to support non-invasive cervical cancer detection technology

Cervical Cancer - Pyruvate kinase isoenzyme tumor can be used as biomarker

Clinical Oncology - Investigators report encouraging results from phase I trial of KRX-0401

Clinical Trial - Company presents favorable results of third phase I KOS-862 trial

Collaborations - Rights licensed for Emory University's noscapine patent portfolio

Colon Cancer - Backstreet Boys singer Kevin Richardson promotes colon cancer

Colon Cancer - Colorectal cancer chemoprevention depends upon clinical trials

Complementary & Alternative Medicine - Fas/FasL system is engaged at pharmacologically significant concentrations

Complementary and Alternative Medicine - Chinese herbs exhibit antitumor effects in mouse lung tumor models

Dendritic Cell Vaccine - Dendritic cell immunotherapy reviewed

Dermatology - Genotype has minimal value for predicting skin cancer formation

Dermatology - Pheomelanins predispose lighter-skinned individuals to developing skin cancer

Diagnostic Imaging - BOLD contrast discerns vascular disruptions after tumor therapy

Diagnostic Imaging - Whole-body MRI detects marrow and extramedullary lesions in lymphoma patients

Diagnostics - A new HPLC assay quantifies the angiogenesis inhibitor SU5416 in plasma

Diagnostics - GTx, Inc., collaborates to develop a diagnostic test for high grade PIN

Diagnostics - Proteomics-based screen identifies disease-associated humoral antigens

Diet and Nutrition - Dietary elements alter the risk for prostate cancer

Drug Resistance - MYC loss inactivates the signals required for doxorubicin-induced apoptosis

Drug Resistance - Novel gene (VanK) required for vancomycin resistance

Endocrinology - Dopamine₂ receptor expressed in 80% of corticotroph pituitary tumors

Endometrial Cancer - Molecular alterations associated with cyclin D1 overexpression in cancer

Enzymology - Secreted matrix metalloprotease 9 has a substantial effect on tumor vascularity

Facilities - Huntsman Cancer Hospital is dedicated in Salt Lake City, Utah

Finance - Hawaii-based pharmaceutical company posts first profit

Finance - Pharmacy company reports increased revenues for the year

Follicular Lymphoma - Combination therapy shows promise in treating "incurable" form of lymphoma

Gastric Cancer - Microarray analysis reveals NOL8 overexpression in diffuse gastric cancer

Gastroenterology - Cirrhosis foreshadows liver cancer in nonalcoholic steatohepatitis patients

Gastroenterology - Contrast-enhanced ultrasound exposes the hemodynamics of liver cancer lesions

Gastrointestinal Cancer - Company selects Insegia as trade name for cancer drug G17DT

Geriatrics - Caring for skin cancer in geriatric patients requires special skill

Geriatrics - Elderly patients with small cell lung cancer receive less aggressive care

Geriatrics - Geriatric patients can undergo cutaneous oncologic and cosmetic surgery

Gynecology - Latent antithrombin could selectively inhibit gynecological malignancies