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Brain Cancer

Cerebral blood flow indices outline glioma vascularity in xenografts

Published in Cancer Weekly, July 13th, 2004

Cerebral blood flow indices outline glioma vascularity in xenografts.

According to recent research from the United States, "continuous arterial spin labeling (CASL) was used to obtain an index of cerebral blood flow (ICBF) in the normal mouse brain and in an orthotopic mouse model of human U87 high-grade glioma at 8.5 T. Under the assumption of a constant tissue:blood partition coefficient for water in different tissues, the mean ICBF (n=14) was found to be 50±9 mL/100g/min for tumor core and 209±11 mL/100g/min for normal tissue."

"The apparent T-1 (T-1app) was 2.01±0.06 sec for tumor core and 1.66±0.03 sec for normal...

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