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Cancer Risk

Rapid rise in PSA level sign of aggressive prostate cancer

Published in Cancer Weekly, July 27th, 2004

Prostate cancer is much more likely to kill if a man's PSA level rises rapidly before the cancer is even diagnosed, according to a study that suggests a new and far more meaningful way of looking at PSA test results.

The finding could help patients and doctors make the often difficult decision of whether to undergo surgery or merely wait and watch.

The PSA test is widely used to diagnose prostate cancer by measuring levels of a substance called prostate-specific antigen in the blood. Up to now, doctors have focused largely on the PSA level itself, and not on how it changes over time.

But researchers at Brigham and Women's Hospital...

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