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Radiation Exposure

Diltiazem prevents gamma radiation-induced anemia

Published in Cancer Weekly, August 10th, 2004

Diltiazem prevents gamma radiation-induced anemia.

"Intraperitoneal administration of diltiazem (DTZ), half an hour prior to whole body gamma irradiation (2.5, 5.0, & 7.5 Gy)," protected animals "from radiation-induced anemia," scientists writing in the Journal of Radiation Research report.

"Radiation exposure significantly (p<.001) reduced the number of pro- and normoblasts in bone marrow and RBC counts, hemoglobin (Hb), hematocrit (Hct), and erythropoietin (EPO) level in blood, but increased myeloid/erythroid ratio.

"At all the radiation doses," said V. Nunia and coworkers, "the maximum decrease in these values was...

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