Prostate Cancer

Link established between key protein and aggressiveness of prostate cancer

Published in Cancer Weekly, August 10th, 2004

Prostate cancer is much more likely to be aggressive if a key protein called Stat5 is found activated and in abundance in the cancer cells, report researchers from Georgetown University's Lombardi Comprehensive Cancer Center. By inhibiting this protein, called Stat5, doctors are exploring how to develop a new treatment strategy for advanced prostate cancer.

The new findings, reported in Cancer Research, show that active Stat5 protein is particularly plentiful in high-histological-grade human prostate cancer. High-histological-grade prostate cancers have often already metastasized by the time of diagnosis and are typically more aggressive in growth.

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Source: Cancer Weekly (2004-08-10)

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