Published in Cancer Weekly, August 10th, 2004
"Tissue hypoxia occurs where there is an imbalance between oxygen supply and consumption in both solid tumors as a result of exponential cellular proliferation and in atherosclerotic diseases as a result of inefficient blood supply," according to researchers in Israel.
"Hypoxia-inducible factor 1 (HIF-1) is central in normal angiogenesis and cancer angiogenesis. HIF-1 is a transcriptional activator composed of an O2 - and growth factor-regulated HIF-1alpha subunit and a constitutively expressed HIF-1beta subunit," noted S.A.M. Paul and colleagues, Tel Aviv Sourasky Medical...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.