Published in Cancer Weekly, August 17th, 2004
Curis, Inc., (CRIS), a therapeutic drug development company, announced that the current online issue of the Proceedings of the National Academy of Sciences of the United States of America contains a study report demonstrating that human medulloblastoma, the most common childhood brain malignancy, is strongly correlated with deletion of a gene that encodes a suppressor of the Hedgehog signaling pathway.
The authors suggest elimination of this suppressor results in abnormal activation of the Hedgehog pathway, thus promoting...
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