Oligodendroglioma

Utility of immunohistochemistry in differential diagnosis determined

Published in Cancer Weekly, August 24th, 2004

The utility of immunohistochemistry in differential diagnosis of clear cell primary brain tumors has been elucidated.

"Clear cell histology is the hallmark of oligodendroglioma (OG) but also characterizes clear cell ependymoma (CCE) and central neurocytoma (CN)," neurologists in Austria explained. "Immunohistochemistry for glial and neuronal proteins may support differential diagnosis."

In their study, O. Koperek and colleagues at the University of Vienna "investigated systematically [the] diagnostic value and limits of immunohistochemistry using representative tumor specimens (>1 cm in diameter) of well-defined OGs, CCEs, and CNs (n=10,...

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Source: Cancer Weekly (2004-08-24)

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