Product Licensing

Hybridon licenses key VEGF patents for treatment of ocular diseases

Published in Cancer Weekly, August 31st, 2004

Alnylam Pharmaceuticals, Inc., (ALNY) and Hybridon, Inc., (HBY) announced that they have entered into an agreement providing Alnylam with an exclusive license to Hybridon's rights to target Vascular Endothelial Growth Factor (VEGF) for ocular indications with RNA interference (RNAi) molecules.

Hybridon has a series of patents and patent applications relating to the therapeutic use of oligonucleotides, including antisense and RNAi compounds, which inhibit the production of the protein VEGF. The VEGF protein has been implicated in cancer and macular degeneration. Hybridon received an upfront payment and is eligible for future milestone payments and royalties.

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Source: Cancer Weekly (2004-08-31)

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