Published in Cancer Weekly, August 31st, 2004
Oncologists in Sweden conducted a study "to evaluate whether the HER2 expression in breast cancer is retained in metastases."
"The HER2 expression in primary tumors and the corresponding lymph node metastases were evaluated in parallel samples from 47 patients," explained J. Carlsson and coauthors at the University of Uppsala Hospital. "The HercepTest was used for immunohistochemical analyses of HER2 overexpression in all cases," while "CISH/FISH was used for analysis of gene amplification in some cases."
"HER2 overexpression (HER2 scores...
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