Carcinogenesis
Fumonisin B-1 encourages liver disease and liver cancer formation
Published in Cancer Weekly, August 31st, 2004
According to published research from South Africa, "fumonisin B-1 (FB1) is a naturally occurring mycotoxin produced by Fusarium verticillioides. Dietary exposure to FB1 has been linked to human cancer in certain parts of the world, and treatment with FB1 causes oval cell proliferation and liver tumors in rats. To study the potential role of oval (liver progenitor) cells in the cellular pathogenesis of FB1-induced liver tumors, we gave male F344 rats prolonged treatment with FB1 for 25 weeks, followed by return to control diet until 50 weeks ('stop study')."
"The time course of...
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Source: Cancer Weekly (2004-08-31)
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