Oncogenesis

Cyclooxygenase 2 is an important regulator of lung cancer pathogenesis

Published in Cancer Weekly, September 7th, 2004

Cyclooxygenase 2 is an important regulator of lung cancer pathogenesis.

According to published research from the United States, "preclinical studies suggest that cyclooxygenase (COX)-2 may be involved in the molecular pathogenesis of some types of lung cancer. Most of the available studies point to its involvement in non-small cell lung cancer. Survival of patients with non-small cell lung cancer expressing high levels of COX-2 is markedly reduced."

"Treatment of humans with the selective COX-2 inhibitor celecoxib augments the antitumor effects of chemotherapy in patients with non-small cell lung cancer. COX-2 has been shown to regulate some aspects...

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Source: Cancer Weekly (2004-09-07)

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