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Ovarian & Endometrial Cancer

L1-based diagnosis, prognosis may improve ovarian, endometrial cancer management

Published in Cancer Weekly, September 7th, 2004

Researchers from Israel found that L1-based diagnosis and prognosis in ovarian and endometrial carcinomas may improve disease management.

M. Fogel and colleagues wrote, "The L1 molecule has emerged as a promising new biomarker for the diagnosis and prognosis of human ovarian and endometrial tumors. It was initially described as an adhesion molecule for neural cells but its function on tumor cells is less well known.

"In this article, the role of L1 in promoting tumor cell adhesion and migration is discussed."

"The question of how L1 determination in tumor tissue samples, serum, and ascites could potentially improve the diagnosis...

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