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Prostate Cancer

Prostate cancer molecular test may address limitations of traditional testing

Published in Cancer Weekly, September 7th, 2004

Molecular testing for a new, highly specific prostate cancer marker may help address some of the well-known limitations of current prostate cancer detection, according to a 517-patient study published in the current issue of the journal UROLOGY.

In the multi-center study, an investigational molecular test called uPM3 gave a correct positive or negative result for the presence of prostate cancer 81% of the time. The uPM3 test detects the presence of a new prostate cancer gene marker called PCA3 in urine. In contrast, traditional prostate cancer detection by measuring total prostate specific antigen levels, or tPSA, had an overall accuracy of 43% or 47% in the...

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