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Gastroenterology

Antiangiogenic agents are important adjuncts to conventional chemotherapy

Published in Cancer Weekly, September 7th, 2004

Antiangiogenic agents are important adjuncts to conventional chemotherapy.

According to recent research published in the European Journal of Cancer, "angiogenesis is an obligatory event for the growth of tumors beyond 2 mm in diameter, above which simple oxygen diffusion can no longer support the rapid proliferation of malignant cells. Angiogenesis is a fine balance between inhibitory and stimulatory factors, the knowledge of which offers novel targets for the treatment of gastrointestinal neoplasia."

"A literature search of PubMed and Medline databases was undertaken, using the keywords colorectal cancer, pancreatic cancer, gastrointestinal...

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