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Carcinogenesis

Key proteins decline in patients with hepatitis C-related liver cancer

Published in Cancer Weekly, September 14th, 2004

Key proteins decline in patients with hepatitis C-related liver cancer.

"Hepatocellular carcinoma (HCC) is a major cause of death in Japan. It has been suggested that hepatitis C virus (HCV) plays an important role in hepatocarcinogenesis, because of high incidence among the patients," according to researchers in Japan.

"To understand the mechanism of hepatocarcinogenesis after HCV infection, we performed a comparative study on the protein profiles between tumorous and nontumorous specimens from the patients infected with HCV by means of two-dimensional electrophoresis," said Y. Yokoyama and colleagues, Yamaguchi University, Department of...

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