Cancer Weekly

Acute Myeloid Leukemia - Genes linked to AML-associated centrosome aberrations identified

Cancer Therapy - Genes causing inherited cancer can help elucidate chemoresistance

Esophageal Adenocarcinoma - Expression of LAT-1 characterized

Glioma Therapy - Radiochemotherapy regimen feasible for preirradiated patients

Lymphoma Therapy - Rituximab with chemotherapy shows promise for splenic MZL treatment

Adverse Drug Effects - Substance P may play role in hypersensitivity reactions induced by paclitaxel

Alopecia - ETG hair-loss treatment technology introduced to Taiwan

Angiology - Angiogenic response is heightened in collagen XVIII/endostatin-null mice

Angiology - Mobile helical computed tomography unit is an accurate predictor

Autoimmunity - Some SCPs are relevant to our understanding of autoimmunity

Awards - Myeloma research group announces 2004 senior Research and Fellows Awards winners

Bladder Cancer - Bladder cancer can be detected with near-infrared imaging techniques

Bladder Cancer - Novel gene therapy for bladder cancer shows strong results in animal studies

Brain Cancer - Protein Smacs back at cancer cells

Brain Cancer - Urokinase receptor ligands spoil glioma growth via antiangiogenesis

Breast Cancer - Breast tumor cells may swell in response to tamoxifen methiodide treatment

Breast Cancer - Breast-conserving surgery plus radiation good for older women, too

Breast Cancer - Circulating tumor cells strongest independent predictor of patient survival

Breast Cancer - MRI more accurate for detecting disease due to BRCA gene mutation

Breast Cancer - MastaScope Eastern European distributor announced

Breast Cancer - Prevention study seeks postmenopausal women at high risk for breast cancer

Breast Cancer - SPECT and pinhole SPECT are advances in axillary lymph node status evaluation

Breast Cancer - Study finds some correlation between IGF-I levels and premenopausal cancer risk

Breast Cancer - Study in human tissue biopsies supports pathogenic role for telomerase

Breast Cancer Awareness - Celebrities flip switch to kick off breast cancer campaign at Las Vegas Venetian

Breast Cancer Therapy - Anti-HER-2 mAbs synergistically kill breast tumor cells

Business Update - Technology upgrade cuts costs, improves earnings for China-based company

COX-2 Inhibitors - Effect of flavonoids and vitamin E on cyclooxygenase-2 transcription reported

Cancer - Calcitriol shows potential as anti-cancer agent

Cancer Development - Psychological factors do not influence cancer development

Cancer Mortality - Fruit, vegetable intake reduces cancer death risk after radiation exposure

Cancer Research - First genetic step necessary for prostate cancer growth identified in research

Cancer Research - Pet models are a valuable part of cancer research

Cancer Risk Factor - Leucomalachite green is mutagenic in female Big Blue B6C3F₁ mice

Cancer Risk Factor - Micronucleus test used on epithelial cells from oral cavity of beedi smokers

Cancer Screening - Popular magazines don't inform men about prostate and colon cancer screening

Cancer Screening - Women starting mammography on time, but failing to follow up

Cancer Therapeutics - Phase I clinical study initiated for novel anti-tumor protein

Cancer Therapy - Advexin cancer therapy featured in Conquest magazine

Cancer Therapy - Cyclacel initiates patient enrollment in third phase I clinical trial of CYC682

Cancer Therapy - J-tipped guidewire suitable for RPCS placement through subclavian artery

Cancer Therapy - Liposomal and standard paclitaxel formulations have comparable efficacy

Cancer Therapy - National Cancer Institute funds cancer therapy development

Cancer Therapy - New patent for compounds delivering drugs directly to tumor granted

Cancer Therapy - Preclinical data demonstrate antitumor effects of T-oligo technology

Cancer Therapy - Sea sponges may yield cancer drug

Cancer Vaccine - NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad immune response

Cell Biology - A new protein is discovered to play a key role in cancer progression

Cell Biology - Actin binding site needed for profilin tumor suppressor activity

Cell Biology - Endoglin blocks transforming growth factor-beta-Smad3 signals

Cervical Cancer - Chemoradiation therapy may benefit patients with periaortic LN metastasis

Cervical Cancer - GCF urges women to request HPV test with annual Pap to detect cervical cancer

Cervical Cancer - Tumor-stromal interactions rule the power of aminopeptidase in cancer invasion

Chemical Hazard - Study shows high levels of dioxin in New Zealand residents near chemical plant

Clinical Trials - High awareness reported for cancer clinical trials advertising section

Clinical Trials - Pharmaceuticals announces phase 1/2 trial of combination lung cancer drug

Coffee Consumption - For the moderate drinker, coffee is safe, according to health publication

Colon Cancer - Enzyme signpost points to better bowel cancer test

Colon Cancer - Phase II trials of TroVax and chemotherapy endpoints reached

Colorectal Cancer -  Wif-1 overexpression linked to pathogenesis

Colorectal Cancer - Phase I/II trial of NV1020 initiated for liver metastases from colorectal cancer

Complementary and Alternative Medicine - The traditional Korean medicine Soamsan has antitumor properties

Continuing Education - Hospital, company provide training for radiation therapy professionals

Data Sharing - Doctors missing out on important information

Dermatology - Oxidative stress in xeroderma pigmentosum fibroblasts characterized

Diagnostics - Digital image analysis tracks antiangiogenic activity in a modified assay

Diet & Nutrition - New research suggests link between maternal diet and childhood leukemia risk

Disease Associations - Human papillomavirus in HIV infection increases risk of pathologic conditions

Disease Associations - K8 gene is expressed in both immediate-early and delayed-early phases of KSHV

Disease Associations - September 11-related cancers may not appear for decades, doctors say

Disease Management - Cancer survivors' other medical problems poorly managed

Drug Development - Collaboration agreement announced on novel therapeutic protein

Drug Development - T-cell lymphoma patients achieve long-lasting responses with human antibody drug

Drug Development - The lipid lowering agent pravastatin may fight cancer

Drug Resistance - Cells with pleiotropic drug resistance can be targeted with anticancer therapy

Endocrinology - Gene expression profiling classifies parathyroid growths

Endometrial Cancer - WT1 and p53 expression vary in serous and endometrioid carcinomas

Environmental Health - Fetus may be affected by environmental pollution, increasing leukemia risk

Epidemiology - Korean-American women need education, access to cancer screening

Familial Hypertrophic Cardiomyopathy - Mutations influencing mRNA could play a role in hypertrophic cardiomyopathy

Finance - Cancer drug development company reports solid financial performance

Fitness & Wellness - City council restricts smoking in St. Paul restaurants and bars

Gene Delivery - Outgrowth endothelial cells host gene vectors that target tumor vessels

Gene Expression - Molecular images track the activity of cancer gene therapy

Gene Suppression - Several strategies eliminate multidrug resistance gene expression

Gene Therapy - RNA interference is a potent tool for gene-specific therapeutics

Gene Transfer - Hypoxia enhances the use of survivin promoter in cancer gene therapy

Gene Transfer - Inflammation constrains a key gene therapy receptor on endothelial cells

Genomic Sequencing - NIH renews contract with Agencourt Bioscience for genomic sequencing services

Genomics and Genetics - Genomic effects of histone deacetylase inhibitors determined in tumor cells

Glioma - Proteome analysis can predict tumor aggressiveness