Myelodysplastic Syndrome

Granulocyte DNA structure models highly predictive of MDS

Published in Cancer Weekly, September 28th, 2004

Novel granulocyte DNA structure models may provide valuable diagnostic and prognostic data for patients with myelodysplastic syndrome (MDS).

In a study from the United States, researchers "used statistical models based on Fourier transform-infrared spectra to differentiate between the DNA structure of normal granulocytes and those obtained" from MDS patients.

"The substantial degree of discrimination achieved between the two DNA groups is attributed to differences in the nucleotide base and backbone structures," reported D.C. Malins and coauthors at the Pacific Northwest Research Institute in Seattle.

"These structural differences...

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Source: Cancer Weekly (2004-09-28)

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