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Drug Development

T-cell lymphoma patients achieve long-lasting responses with human antibody drug

Published in Cancer Weekly, September 28th, 2004

Genmab A/S announced that cutaneous T-cell lymphoma (CTCL) patients in the HuMax-CD4 phase 2 studies achieved long-lasting responses, with an average response duration of more than 6.6 months.

This duration of response data is based on an analysis of responding mycosis fungoides (MF) patients at all dose levels, 280, 560 and 980 mg.

In addition, median time to disease progression of all 38 MF patients in the 2 phase 2 studies is more than 5.7 months. Disease progression is defined as an increase in disease that is more than 25% above the baseline measurement taken when patients entered the study.

The average duration of response...

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