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Liver Cancer

Tumor genes cluster into two subsets that correlate to survival

Published in Cancer Weekly, October 5th, 2004

An analysis of the gene expression patterns of 91 unrelated liver tumors revealed two distinctive subclasses highly associated with patient survival, according to a new study.

The study is among the first to explore the complete molecular pathogenesis of hepatocellular carcinoma (HCC). It identified expression profiles of a limited number of genes that accurately predicted length of patient survival, and these findings may open the door to the development of more targeted therapies for liver cancer patients.

While gene technology has previously been applied to some specific aspects of liver cancer, researchers led by Dr. Snorri Thorgeirsson of the...

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