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Cancer Therapy

Double drug combo attacks tumor and blood vessel development

Published in Cancer Weekly, October 5th, 2004

Cancer researchers have long suggested that new targeted drugs may work best when paired with other therapies.

In a new study published in Cancer Research, scientists have taken some of the first steps to demonstrate this synergy in mouse and cell line models.

The findings show that two different drugs may work better in a "one-two punch," targeting a cancer development process in two types of cells. The early results are so promising that preliminary testing of the drug combination in humans is now being planned.

"Anti-angiogenesis" drugs, which inhibit vast networks of blood vessels that feed tumors, have thus far failed...

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