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Stem Cell Research

Endothelial SCs create microvascular networks within tissue-engineered construct

Published in Cancer Weekly, October 12th, 2004

Endothelial progenitor cells may be used to create microvascular networks within tissue-engineered constructs.

According to investigators in the United States, "Tissue engineering may offer patients new options when replacement or repair of an organ is needed. However, most tissues will require a microvascular network to supply oxygen and nutrients."

"One strategy for creating a microvascular network would be promotion of vasculogenesis in situ by seeding vascular progenitor cells within the biopolymeric construct. To pursue this strategy," wrote X. Wu and colleagues, "we isolated CD34+/CD133+ endothelial progenitor cells (EPC) from human umbilical...

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