Published in Cancer Weekly, October 12th, 2004
"To clarify the genetic aberrations involved in the development and progression of hepatitis C virus-associated hepatocellular carcinoma (HCV-HCC), we investigated DNA copy number aberrations (DCNAs) in 19 surgically resected HCCs by conventional comparative genomic hybridization (CGH) and array CGH," scientists in Japan reported.
"Conventional CGH revealed that increases of DNA copy number were frequent at 1q (79% of the cases), 8q (37%), 6p (32%), and 10p (32%) and that decreases were frequent at 17p (79%),16q (58%), 4q (53%),13q (42%), 10q (37%), 1p (32%), and 8p (32%)....
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