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Tumor-associated macrophages and blood factor prognosticate colorectal cancer

Published in Cancer Weekly, October 19th, 2004

Tumor-associated macrophages and blood factor prognosticate colorectal cancer.

According to published research from Austria, "tumor-associated macrophages (TAM) are involved in tumor angiogenesis and anti-tumor immune response. In colorectal cancer (CRC), an association of high microvascular density (MVD) and unfavorable prognosis has been reported by some investigators. However, heterogeneous patient groups were studied."

"We, therefore, analyzed the correlation between TAM and MVD and the prognostic relevance of MVD, TAM and T lymphocyte infiltration for long-term survival in a homogeneous group of 70 patients with moderately differentiated cancers...

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