Lung Cancer

Myotubularin-related protein suppresses growth of lung carcinoma cells

Published in Cancer Weekly, October 26th, 2004

Myotubularin-related protein suppresses the growth of lung carcinoma cells.

"We report that the human myotubularin-related protein (KIAA0371) induced growth suppression of lung cancer cells.

"Colony formation assays demonstrated that the exogenous expression of the human myotubularin-related gene induced a significant growth inhibition of H1299 cells in which the expression of the human myotubularin-related gene was undetectable," wrote scientists in South Korea.

"Colony formation of these cells was reduced by 39% after transfection with this gene, as compared with the control vector. Cells stably transfected with this gene showed...

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Source: Cancer Weekly (2004-10-26)

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