Breast Cancer

Basal-like breast tumors characterized

Published in Cancer Weekly, October 26th, 2004

The immunohistochemical and clinical features of basal-like breast tumors have been determined.

"Expression profiling studies classified breast carcinomas into estrogen receptor (ER)⁺/luminal, normal breast-like, HER2 overexpressing, and basal-like groups, with the latter two associated with poor outcomes," oncologists in the United States explained.

"Currently, there exist clinical assays that identify ER⁺/luminal and HER2-overexpressing tumors," noted T.O. Nielsen and colleagues at the University of North Carolina, who "sought to develop a clinical assay for breast basal-like tumors."

"To identify an...

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Source: Cancer Weekly (2004-10-26)

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