Stem Cell Transplantation
Donor lymphocyte infusions induce graft-versus-myeloma effect after ASCT rescue
Published in Cancer Weekly, November 2nd, 2004
According to a study from the United States, "In an attempt to induce a graft-versus-myeloma effect, we administered donor lymphocyte infusions (DLI) after high-dose therapy with autologous stem cell transplant rescue to seven patients with refractory or relapsed multiple myeloma.
"High-dose therapy consisted of melphalan, idarubicin and etoposide (days -9 to -6) followed by autologous stem cell infusion on day 0. DLI (five of seven donors with two or three HLA antigens mismatched) were administered...
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Source: Cancer Weekly (2004-11-02)
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