Breast Cancer
Genetic tumor virulence markers identified in murine model
Published in Cancer Weekly, November 2nd, 2004
"FVB/N-Tg (MMTV-PyMT)634Mul-transgenic mice develop multifocal mammary tumors with a high incidence of pulmonary metastasis," according to oncologists in the United States, who "demonstrated previously that mammary tumors derived from transgene-positive F1 progeny - in particular inbred strains - display altered latency, tumor growth rates, and metastatic rates when compared with the FVB/NJ homozygous parent."
"To identify genes with expression that might be critical in modifying the biological behavior of MMTV-PyMT tumors," T.H. Qiu and colleagues...
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Source: Cancer Weekly (2004-11-02)
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