Gastric Cancer

Gene profiling can distinguish intestinal and diffuse carcinomas

Published in Cancer Weekly, November 2nd, 2004

Gene expression profiling may be useful for differentiating between intestinal and diffuse gastic cancers.

"Gastric cancer is the fourth leading cause of cancer-related death in the world," according to oncologists in Japan. "Two histologically distinct types of gastric carcinoma, 'intestinal' and 'diffuse', have different epidemiological and pathophysiological features that suggest different mechanisms of carcinogenesis."

"A number of studies have investigated intestinal-type gastric cancers at the molecular level, but little is known about mechanisms involved in the diffuse type, which has a more invasive phenotype and poorer prognosis," noted N....

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Source: Cancer Weekly (2004-11-02)

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