Cancer Weekly

Breast Cancer - Childhood cancer survivors at increased risk of breast cancer

Cancer Screening - Pap test screening is a challenge in Canada for those serving immigrants

Gynecology - Overexpressed p53 correlates with the aggressiveness of endometrial cancer

Pathological Angiogenesis - Endothelial cells may be resistant to fibroblast growth factor

Rhabdomyosarcoma - Mice engineered with condition mimicking deadly muscle cancer

Adverse Drug Effects - ART drugs pose potential cancer hazard to exposed children

Apoptosis - Oxidative stress and caspase activation involved in paclitaxel-induced apoptosis

Apoptosis - c-Src kinase helps regulate TGF-beta 1-induced apoptosis

Assisted Reproduction - Drug protocols for IVF compared in breast cancer patients

Assisted Reproduction - Researchers study ways to protect breast cancer patients' future fertility

Awards - Couric presented with multiple myeloma leadership award

Behavior Intervention - Stage-matched expert systems can produce behavior changes in at-risk populations

Brain Stem Glioma - Brain tumor survivors visit research institute

Breast Cancer - Advanced breast cancer imaging technology takes step closer to market

Breast Cancer - Breast cancer imaging system delivered to Italy's National Tumor Institute

Breast Cancer - Chemopreventive properties of pomegranate extracts studied in murine model

Breast Cancer - Combination HRT doubles breast density, quadruples risk of abnormal mammograms

Breast Cancer - Ductal lavage may not detect disease

Breast Cancer - Enrollment of MammoSite patient registry completed

Breast Cancer - Lee National Denim Day raises $7.6M for breast cancer research, programs

Breast Cancer - Loss of PTEN expression infrequent

Breast Cancer - National Park Service upset over plan to illuminate St. Louis' Gateway Arch

Breast Cancer - Ninety-seven grants awarded to breast cancer scientists and researchers

Breast Cancer - No link between conjugated linoleic acids and disease found

Breast Cancer - P53 and MUC-1 may predict treatment efficacy and outcome in patients with IBC

Breast Cancer - PTEN loss in invasive ductal carcinoma of the breast predicts poor survival

Breast Cancer - Passage of Mammography Quality Standards Reauthorization Act of 2004 lauded

Breast Cancer - Pharmaceutical company gains FDA clearance for cancer drug Provecta

Breast Cancer - Promoter methylation of PTEN gene is common molecular change in breast cancer

Breast Cancer - Study examines reasons for late-stage disease

Breast Cancer - Study finds no link between tamoxifen and stroke

Breast Cancer - Survivor creates mammogram reminder rings

Breast Cancer - U.S. NIH study seeks 50,000 sisters of women with breast cancer

Breast Cancer - Vegetables negatively associated with breast cancer in postmenopausal women

Breast Cancer Vaccine - Vaccine for prevention of HER2 mammary carcinomas under development

Business Update - Information technology company announces new contracts

Business and Finance - Imaging company reports 2004 results and appoints new CEO

Cancer & Pregnancy - Doctors report safer ways to help cancer patients have children

Cancer Epidemiology - Hmong face high rates of some cancers

Cancer Growth Factors - Beta-defensins and VEGF-A nurture tumor neovascularization

Cancer Screening - Developer of liquid-based Pap test awarded 5-year contract in Liverpool U.K.

Cancer Screening - Urine testing might prove to be an alternative screening test

Cancer Therapy - Discovery might improve design, effectiveness of anticancer drugs

Cancer Therapy - Epigenome manipulation turns off as many genes as it turns on

Cancer Therapy - FK228 gets fast-track designation for cutaneous T cell lymphoma

Cancer Therapy - High school swimmer fights cancer into remission

Cancer Therapy - Hyperforin keeps cancer invasion and metastasis in check in animal studies

Cancer Therapy - Imatinib sensitivity predicted by testing Wilms tumor gene expression

Cancer Therapy - Novel transplatinum drug ATZ interferes with topoisomerase I in cancer cells

Cancer Therapy - PTEN deficiency predicts trastuzumab resistance in breast cancer patients

Cancer Therapy - Protein found to block anticancer drug access, reducing ability to reach tumors

Cancer Therapy - Scientists studying a "nano-bullet" for noninvasive treatment of cancer tumors

Cancer Therapy - Toledo Clinic Inc., Detroit-based cancer institute announce alliance

Cancer Therapy - Tumor necrosis factor alpha sensitizes malignant cells to chemo drugs

Cancer Vaccine - CD4+CD25+ T cells are preferentially induced by vaccine vector

Cancer Vaccine - Cancer immunotherapy beyond current vaccines reviewed

Cancer Vaccine - GM-CSF vaccines impair immune response via myeloid suppressor cells

Cancer Vaccines - Nano-vaccines exhibit therapeutic and protective effects against tumors

Carcinogenesis - Lessons from DES use help researchers predict other perinatal cancer risks

Cell Biology - Newly discovered protein suggests novel tumorigenic pathway

Cervical Cancer - Evidence lacking for concomitant use of hydroxyurea plus radiotherapy

Cervical Cancer - Specimen adequacy crucial for proper diagnosis of ASCUS

Chemosensitization - A new multicomponent drug delivery system sensitizes lung cancer to therapy

Childhood Leukemia - U.S. CDC trains workers to take biosamples

Chronic Myeloid Leukemia - BCR-ABL transcripts early predictors for hematological relapse in CML after HSCT

Colon Cancer Risk Factor - Program improves colorectal cancer prevention among African Americans

Colorectal Cancer - Cancer progression depends on TGF-b production in T lymphocytes

Colorectal Cancer - Doctors can improve colorectal cancer screening rates

Cord Blood Transplantation - Patients over 45 years old without suitable BM donors may be candidates for CBT

Dendritic Cell Vaccine - Alpha-type-1 polarized dendritic cells optimize CTL-inducing activity

Depression - Future antidepressants may target the immune system

Dermatology - Stat3 is required for the onset of epithelial carcinogenesis

Diagnostics - A diagnostic biochip conducts analysis of MLL translocations in acute leukemia

Diagnostics - Antitumor response visualized by fluorescent molecular tomography

Diagnostics - Bioassays company announces U.S. Army contract, new kinase Activity Assays

Diet & Nutrition - Excess dietary omega 6 speeds breast cancer by altering gene activity

Drug Delivery - Liposomal cisplatin has reduced renal toxicity in animals

Drug Development -  Streblus asper volatile oil has anti-leukemia activity

Drug Development - New agents show promise for blocking tumor vascularity by targeting VEGF

Drug Development - Novel synthetic epothilones show promising anticancer activity

Endocrinology - Real-time PCR simultaneously analyzes numerous steroidogenic enzyme expressions

Environmental Health - Air monitors detect toxin near Baton Rouge, Louisiana

Environmental Health - Major U.K. poultry producer finds cancer-causing drug in chicken

Environmental Health - Report: Hispanics more exposed to environmental health risks

Environmental Health - World Wildlife Fund blood test finds cocktail of chemicals in 14 E.U. ministers

Enzymology - Bmx distorts inflammatory processes in transgenic mice

Enzymology - Telomerase-immortalized endothelial cells are valuable for angiogenic research

Epstein-Barr Virus - Immune responses against Epstein-Barr virus are varied

Erythropoiesis - Beta-galactosidase useful marker to detect definitive erythropoiesis after SCT

Finance - Biotech listed as one of Maryland's fastest-growing technology companies

Finance - Cancer vaccine maker reports loss of $0.54 per share

Finance - Cell-focused company execs adopt rule 10b5-1 prearranged stock sales plans

Finance - Oncology drug development company reports third quarter financial results

Finance - Photodynamic therapy company receives $15 million line of credit

Gastric Cancer Vaccine - OK-432 after surgery for gastric cancer did not improve survival rate

Gastroenterology - Pharmaceutical company announces positive results of Balsalazide study

Gastrointestinal Cancer - Diabetes hikes risk for liver, pancreatic cancers

Gene Mutation - Mutation hotspots in p53 gene depend on tumor type and cell growth conditions

Gene Research - Mutations toward the 3' end of MYH7 cause early-onset distal myopathy

Gene Research - Somatic mutations in genes of cardiac cells provide a novel mechanism of disease

Genomics and Genetics - Utility of BAC arrays reviewed

Genomics and Genetics - Utility of microarrays in cytogenetic analysis reviewed

Gynecologic Cancers - Psammoma bodies in cervicovaginal smears require investigation

Gynecological Cancer - Antibodies for p53 may aid differential diagnosis

Gynecological Oncology - The enzyme inhibitor zoledronic acid thwarts cervical carcinogenesis

HIV/AIDS Quality of Life - HIV/AIDS effect on life expectancy in the United States updated

HIV/AIDS-Related Kaposi Sarcoma - HAART plus pegylated liposomal doxorubicin effective in Kaposi sarcoma

Head and Neck Cancer - Estrogen metabolite enhances protein transduction therapy in oral cancer cells

Head and Neck Cancer - Study confirms link between cancer and common Asian nut

Heart Disease - Mutation of HEY2 is not a major factor in congenital heart disease

Hepatitis C - Virus linked to non-Hodgkin lymphoma

Herpesvirus - DNA vaccine trial initiated for treatment of herpes simplex type 2