Published in Cancer Weekly, November 9th, 2004
According to a recent study in Cancer Treatment Reviews, "We identified eight randomized control trials of hydroxyurea and radiation versus radiotherapy alone (six published in full and two abstracts). Most concluded that outcomes were improved by use of hydroxyurea. However, methodological problems associated with these trials included small sample size, a large number of patient exclusions post-randomization, differing outcome definitions, subgroup analyses of already small numbers of patients and questionable rules for censoring,...
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