Head and Neck Cancer
Suicide gene therapy and radiation kill nasopharyngeal carcinoma xenografts
Published in Cancer Weekly, November 23rd, 2004
According to a study from the Peoples Republic of China, "nasopharyngeal carcinoma (NPC) is very common in Southern China and Southeast Asian countries. To explore a novel and more effective approach to NPC therapy, a combined strategy of suicide genes and radiation was designed in this study. Five suicide gene expression cassettes, yeast CD, yeast CD/UPRT, and yeast CDglyTK gene controlled by CMV, and Egr-1 and a synthetic CMV-enhanced Egr-1 promoter (CE) were constructed in an expression vector p11MS."
"The expression of suicide genes in NPC CNE-2 cells were detected by...
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Source: Cancer Weekly (2004-11-23)
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