Autoimmune Hemolytic Anemia

High incidence of autoimmune hemolytic anemia complicating SCT in children

Published in Cancer Weekly, December 7th, 2004

There is a high incidence of autoimmune hemolytic anemia complicating stem cell transplantation in pediatric patients.

"Hemolytic anemia is a recognized complication of hematopoietic cell transplantation (HCT) and can result from alloimmune- or autoimmune-derived antibodies. Unlike alloimmune hemolytic anemia, autoimmune hemolytic anemia (AIHA) is poorly understood, particularly in the pediatric population where only case reports have been published.

"Between January 1995 and July 2001, 439 consecutive allogeneic HCT were performed in pediatric patients at the University of Minnesota, 31% (n=136) from related donors (RD) and 69% (n=303) from...

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Source: Cancer Weekly (2004-12-07)

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