Brain Cancer

Post-therapy damage in medulloblastoma patients can be mistaken for new tumors

Published in Cancer Weekly, December 7th, 2004

Irradiation and high-dose chemotherapy used to treat two types of brain tumors - medulloblastoma and supratentorial PNET - can cause changes in the brain's white matter that look like tumors when seen on MRI scans.

This finding, by a team of investigators led by St. Jude Children's Research Hospital, was published in the Journal of Clinical Oncology.

White matter is the part of the brain composed of nerves that are covered in a pearly-white sheath. Much of the cerebral cortex, where high-level thinking occurs, is made of white matter.

The study demonstrates that this damage, called white matter lesions (WMLs), can be...

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Source: Cancer Weekly (2004-12-07)

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