Cancer Weekly

Free Radicals - Fullerene C₆₀ functionally replaces mitochondrial Mn superoxide dismutases

Gastroenterology - NK4 staunches gastric cancer-related peritoneal metastasis in mice

Gene Transfer - Therapy combining adenovirus vectors has increased transduction efficiency

Glioma - Glioma ezrin expression has prognostic value

Graft-versus-Host Disease - Chronic GvHD suppresses relapse in CML and ALL but not in AML

Head and Neck Cancer - Gene assays back up sentinel node navigation surgery in oral cancer patients

Head and Neck Cancer - Report seeks improved management of head and neck cancers

Healthcare Funding - Tobacco-tax backers fighting pre-emptive legislation

Hormone Therapy - Researchers continue to weigh in on estrogen monotherapy arm of WHI study

Human Papillomavirus Vaccine - HPV-like particles encapsidating IL-2 adjuvant enhanced immunogenicity

Immunology - Eosinophils secrete plasminogen activator inhibitor-2

Immunology - Local blockade of negative stimulatory molecules augments antitumor cytokines

Information Technology - Grid software developer selected by IBM to power world community research grid

Intraductal Carcinoma - Microvessel phenotypes are altered in pre-invasive breast lesions

Leukemia - Mast cell neoplasms may respond to target-specific approaches

Leukemia - Umbilical-cord blood works well against leukemia in adults as well as children

Liver Cancer - Company presents liver cancer treatment at vascular targeting agents meeting

Lung Cancer - Early results shed light on lung cancer screening advance

Lung Cancer - Long-term smokers avoid lung cancer risk if they quit smoking

Lung Cancer - S100A2 expression characterized in NSCLC tumors and normal cells

Lung Cancer - Utility of FDG-PET in workup reviewed

Lymphoma - Arthritis treatment may reactivate virus responsible for some lymphomas

Lymphoma - NK cells induce resistance to cytotoxic chemotherapy in B lymphoma cells

Mantle Cell Lymphoma - Rituximab plus thalidomide effective for relapsed/refractory MCL

Metastasis - Reovirus foils the growth of metastatic breast cancer brain lesions

Natural Products - beta-HIVS suppresses TNF receptor-associated protein 1 gene expression

Neurology - Combined gene therapy and cancer immunotherapy attack glioma in murine models

Nutrition - Antioxidant supplementation may reduce incidence of cancer in men

Nutrition - Group questions conclusions in recent vitamin E meta-analysis

Obesity - Excess weight tied to increased risk for dozens of conditions

Oncology - Biotech company announces commercial supply agreement for cancer treatment

Oncology - Biotech company announces initiation of Phase II trial for cancer treatment

Oncology - EXACT Sciences broadens relationship to include PIK3CA colorectal cancer marker

Oncology - Estrogen receptor beta makes breast cancer cells susceptible to retinoic acid

Oncology - Government, academic, medical collaboration launches Spanish cancer program

Oncology - Interleukin-6 may favor tumor-host interactions in uveal melanoma

Oncology - Matrix enzyme inhibitor predicts poor outcomes for esophageal cancer patients

Oncology - New census shows growth in PET/CT installations

Oncology - Perillyl alcohol inhibits angiogenesis

Oncology - Platelet activation shifts the angiogenic balance in cancer patients

Oncology - U.S. FDA accepts Onco-LIFE PMA supplement for filing

Oral Squamous Cell Carcinoma - Gene expression profile of invasive tumors characterized

Ovarian Cancer - CPT-11 plus mitomycin C may work against platinum-refractory disease

Paraneoplastic Neurologic Disorders - Pyridoxal phosphatase is a novel cancer autoantigen in the central nervous system

Patents - U.S. Patent issued for peptide used to diagnose, treat neuroectodermal tumors

Pediatric Health - Children's hospital launches Thanks & Giving campaign to fight childhood disease

Personnel - Cancer-focused biotech company names Rick Hamm general counsel

Personnel - Dean J. Mitchell appointed president and CEO of AGGRASTAT maker

Personnel - Oncology company announces change in senior management

Personnel - Tim Germann named VP of sales and marketing by genomics diagnostics company

Prostate Cancer - Coding sequence determined for orthologs of prostate cancer susceptibility gene

Prostate Cancer - First-ever Cs-131 brachytherapy seeds to treat prostate cancer implanted

Prostate Cancer - Ovine atadenovirus guides gene-directed enzyme prodrug therapy to cancer cells

Prostate Cancer - Primary tumor-derived human prostate cancer cells retain neoplastic phenotypes

Prostate Cancer - Provenge data: Vaccine therapy for prostate cancer is shown to extend survival

Pyomyositis - Bacterial pyomyositis increasing in HIV and non-HIV infected patients in the US

Radiation Poisoning - Chernobyl disaster caused cancer cases in Sweden

Renal Cell Carcinoma - HIF1A gene polymorphisms associated with renal cell carcinoma phenotype

Restructuring - Pharmaceutical company announces plan to discontinue gene editing operations

Selenium - Bioavailable selenium not preferentially toxic to transformed hepatocytes

Stem Cell Research - Bryostatin-1 enhances maturation/antigen-presenting ability of dendritic cells

Stem Cell Research - Gfi-1 restricts proliferation and preserves functional integrity of HSCs

Stem Cell Transplantation - Alpha-erythropoietin + filgrastim improves outcome/cost balance of ASCT

Stem Cell Transplantation - Majority of SCT patients accept poor QOL for small chance of cure

Stem Cell Transplantation - Megakaryocyte engraftment follows reduced-intensity conditioning

Stem Cell Transplantation - Stem cells from donors with abnormal findings can be used for HCT

Stock Market - Cancer diagnostics company announces new stock symbol, name

Tobacco Use - Duke University study finds cigarettes cost a total of $40 a pack

Tobacco Use - Percentage of smokers increases in Alabama

Tobacco Use - Sioux City, Iowa, bans smoking on sidewalks near clinics

Transfusion - Report provides suggestions for blood transfusions for terminal patients

Tumor Pathology - Stromal VEGF is a diagnostic biomarker in mammary phyllodes tumors

Vaccine Development - IFN-gamma enables cross-presentation of protein antigen in Langerhans cells

Vaccine Development - Naked sequence-stabilized mRNA vaccine generates immunity to diverse antigens

Vaccine Development - Protein to antigen fusion heightens the efficacy of DNA cancer vaccine