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Brain Cancer
Cytokine gene therapy may overcome common barriers to glioma immunotherapy
December 28th, 2004
Cytokine gene therapy may overcome common barriers to glioma immunotherapy. "Despite advances in surgical and adjuvant therapy, the prognosis for malignant gliomas remains dismal. Malignant gliomas, like other malignancies, are able to overcome host immune defenses through a variety of mechanisms that have become increasingly well-characterized over the past decade. However, this 'immunologically privileged' status of the brain is not absolute," researchers in the United States report. "Systemic immunization with brain-specific antigens can induce immune responses that are manifested in the central nervous system (CNS), such as experimental allergic...
Source: Cancer Weekly (2004-12-28)
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