Vaccine Development
Fused heat shock proteins do not guarantee the success of DNA vaccines
Published in Cancer Weekly, December 28th, 2004
According to recent research published in the journal Cancer Immunology Immunotherapy, "the ability of heat shock proteins (HSPs) to increase the potency of protein- and DNA-based vaccines has been previously reported. We have constructed several plasmid-based vectors encoding chimeric proteins containing prostate-specific antigen (PSA) fused to Mycobacterium tuberculosis hsp70, M. bovis hsp65, Escherichia coli DnaK (hsp70), or human hsp70."
"Immunizing mice with these plasmids induced CD8+cytotoxic T lymphocytes (CTLs) specific to human PSA and...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2004-12-28)
More Articles from Cancer Weekly
- Breast Cancer
Scientists find way to see breast cancer activity from outside the body - Colorectal Cancer
Association of nut and seed intake with cancer risk studied - Esophageal Cancer
Genes involved in zinc-induced tumor cell apoptosis identified - Gynecology
Simultaneous blockade of Bcl-2 and DNA repair staunches ovarian cancer growth - Lung Cancer
Potential genetic biomarkers of NSCLC identified - Acute Lymphoblastic Leukemia
U.S. FDA committee recommends accelerated clofarabine approval for ALL - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
