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Esophageal Cancer
Genes involved in zinc-induced tumor cell apoptosis identified
December 28th, 2004
Genes involved in zinc-induced apoptosis of esophageal tumor cells have been identified. "Zinc deficiency (ZD) in rats increases esophageal cell proliferation and the incidence of N-nitrosomethylbenzylamine-induced esophageal tumors," scientists in the United States explained. "Conversely, zinc replenishment (ZR) rapidly induces apoptosis in esophageal epithelia and reverses cancer development." In a recent study, H. Ishii and coauthors at Thomas Jefferson University in Philadelphia "investigated gene expression changes in ZR versus ZD esophageal epithelia to identify differentially expressed genes associated with the antitumor effect of...
Source: Cancer Weekly (2004-12-28)
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