Cancer Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cancer Genetics
Mutation panel described for screening BRCA1/2 mutations in French Canadians
December 28th, 2004
Researchers with the Montreal General Hospital reported in 1998 "that a significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor specific germline mutations in BRCA1 or BRCA2 attributed to common founders." Now, in a paper in the International Journal of Cancer, the team has determined "the frequency of previously described mutations (n=7) and 13 mutations identified in French Canadian families since 1998, in a new group of families (n=88)." K.K. Oros and colleagues reported, "Four of the previously described mutations, 4446C > T, 2953delGTAinsC, 8765delAG, and 6085C > T, account for 72% and 69%...
Source: Cancer Weekly (2004-12-28)
|
