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Cancer Research
HSPB9 is a cancer/testis antigen; it may interact with dynein subunit TCTEL1
December 28th, 2004
Testis-specific human small heat-shock protein HSPB9 is a cancer/testis antigen, and it may interact with the dynein subunit TCTEL1. According to recent research from Netherlands, "Searching EST databases for new members of the human small heat shock protein family, we recently identified HSPB9, which is expressed exclusively in testis as determined by Northern blotting (Kappe et al., Biochim. Biophys. Acta 1520, 1-6, 2001)." "Here we confirm this testis-specific expression pattern by RT-PCR in a larger series of normal tissues. Interestingly, while screening HSPB9 ESTs, we also noted expression in tumors, which could be verified by RT-PCR. Protein...
Source: Cancer Weekly (2004-12-28)
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