Cancer Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Apoptosis
Cannabinoid dexanabinol inhibits NF-kappa B
December 28th, 2004
Dexanabinol, a cannabinoid, inhibits NF-kappa B. "Exogenous and endogenous cannabinoids have been shown to have neuroprotective effects in vitro and in vivo. Although many of the pharmacological effects of cannabinoids have been identified, the mechanism of neuroprotection still represents a controversy. "Here we demonstrate for the first time protective effects of the synthetic cannabinoid dexanabinol by inhibiting apoptosis in a neuron-like cell line using nuclear staining and FACS analysis and in primary neurons," scientists in Germany report. "We provide further evidence of inhibition of nuclear factor-kappakappa B (NF-kappaB)...
Source: Cancer Weekly (2004-12-28)
|
