Non-Hodgkin Lymphoma

Genasense shown to enhance the antilymphoma activity of Velcade and Rituxan

Published in Cancer Weekly, January 11th, 2005

Genta, Inc., (GNTA) announced that two new studies have shown that Genasense (oblimersen sodium) Injection, the company's lead anticancer drug, showed synergistic activity with both bortezomib (Velcade; Millennium Pharmaceuticals, Inc.) and rituximab (Rituxan; Genentech, Idec) in experimental models of B-cell non-Hodgkin lymphoma (NHL).

The data were presented in sessions at the annual meeting of the American Society of Hematology in San Diego, California.

In the first study, investigators from Roswell Park Cancer Institute showed that Genasense or rituximab used alone significantly increased mean survival of mice implanted with NHL (by 130% and...

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Source: Cancer Weekly (2005-01-11)

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