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Proteomics

Fetuin-B overexpression halts murine tumor activity

Published in Cancer Weekly, January 11th, 2005

Fetuin-B overexpression halts murine tumor activity.

"Studies of mouse models for multistage carcinogenesis have led to the identification of a susceptibility locus for skin tumor development (Skts9) in the proximal region of mouse chromosome 16. This chromosome region shows a loss of heterozygosity or an allelic imbalance in mouse skin and pancreatic islet carcinoma, and has been associated with angiogenesis," according to researchers in the United States.

"The microsatellite marker D16Mit2, which has the strongest linkage to skin tumor susceptibility, was used to screen a bacterial artificial chromosome (BAC) library, leading to the identification...

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