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Stem Cell Transplantation

IL-8 may play important role during engraftment after hematopoietic SCT

Published in Cancer Weekly, January 11th, 2005

IL-8 may play an important role during engraftment after hematopoietic stem cell transplantation.

According to recent research from Germany, "We studied the role of interleukin (IL)-8 during engraftment after hematopoietic stem cell transplantation.

"In 40 consecutive patients undergoing either allogeneic marrow (n=32) or autologous peripheral blood stem cell transplantation (n=8), IL-8 plasma levels were serially determined. Median IL-8 concentrations peaked during the neutropenic phase and, subsequently, subsided to pretransplant levels in patients achieving engraftment."

"In all patients, we observed an inverse correlation of...

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