Cancer Weekly
Susan Hasty, Publisher
Table of Contents . . . January 18th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cancer Weekly | Other Publications
Breast Cancer - Cancer detected by screening mammography associated with less toxic therapy
Cancer Genetics - BRCA1 mutation prevalence in ovarian tumors is low in Norway
Cancer Therapy - Riddelliine mutagenicity different in liver endothelial and parenchymal cells
Colon Cancer - Chemotherapy useful for liver metastases from colorectal cancer
Hepatocellular Carcinoma - Dendritic cells elicit T-cell-mediated immune responses to HCA587 protein
Acute Myeloid Leukemia - Genes with prognostic value identified in childhood AML with FLT3 mutations
Antitumor Therapy - Bacteriolytic therapy generates immune response against experimental tumors
Awards - Women's cancer journeys honored at Oncology on Canvas competition in London
Biliary Tract Cancer - S-1 demonstrates antitumor activity in biliary tract cancer
Biotechnology - Antimutagenic and antioxidative effects of green tea components clarified
Bone Fibrosarcoma - Genetic profile determined through chromosome CGH and DNA microarrays
Brain Cancer Vaccine - Human leukocyte antigen-A24-restricted antitumor cell generated
Breast Cancer - Andrologists review risk factors and diagnosis for breast cancer in men
Breast Cancer - Automatic boundary detection method for mammographic masses developed, tested
Breast Cancer - Better quality of life reported after sentinel node biopsy
Breast Cancer - CD8+ T cells from breast cancer patients recognize mammaglobin epitopes
Breast Cancer - Clinical trial of new 3D mammography system initiated
Breast Cancer - Data presented on high-dose weekly Abraxane
Breast Cancer - Factors associated with decreased screening use identified from WHI study
Breast Cancer - Germline sequence variation in CHEK2 gene screened in male breast cancer
Breast Cancer - Matrix metalloproteinases are prognostic in patients with breast cancer
Breast Cancer - Model of growth may help psychosocial treatment in breast cancer survivors
Breast Cancer - New test can predict risk of breast cancer recurrence
Breast Cancer - Premenopausal status and combined effect of three genotypes increases risk
Breast Cancer - Researchers present results of epidemiologic study of breast cancer test
Breast Cancer - Serum levels of IGF-I higher in women with breast cancer history
Breast Cancer - Study may revise clinical approach to invasive lobular breast carcinoma
Breast Cancer - Toremifene provides better profiles of lipid metabolism compared to tamoxifen
Breast Conservation Therapy - Breast conservation therapy may warrant plastic surgery consultation in protocol
Business & Finance - Surgical technology company announces issuance of financing
Business Update - Cancer vaccine developer establishes new operations in the U.S.
Business Update - Drug discovery company announces partnership with Schering AG
Business Update - National system of prevention centers launched
Business Update - Pharma company acquires intellectual property right in immunotherapy
Cancer Awareness - Sioux Falls, Michigan, bishop has battled cancer
Cancer Genetics - Women's satisfaction with BRCA1/2 genetic counseling varies
Cancer Research - Biopharma company initiates phase I trial for MGCD0103
Cancer Research - Cancer centers get $13.4 million for research
Cancer Research - Ingredient in cranberries provide key anticancer compound
Cancer Research - Investigational new drug application filed for pro-apoptotic cancer candidate
Cancer Research - New drug fights blood cancer patients' mouth and digestive tract mucositis
Cancer Research - Pharma company receives approval for phase 1 trial of anticancer antibody
Cancer Research - Research shows drug combination promising for leukemia treatment
Cancer Risk Factor - Fatty acids and exercise affect glucose transport but not tumor growth
Cancer Risk Factor - High cholesterol levels weaken breast cancer metastasis
Cancer Risk Factors - LPL gene polymorphisms associated with prostate cancer risk in Japanese study
Cancer Risk Factors - PIG3 polymorphism not linked with increased cancer risk in study
Cancer Risk Factors - Study results indicate activation of c-Met in gastric carcinoma tissue
Cancer Risk Factors - Telomere loss can generate chromosome rearrangements associated with cancer
Cancer Survival - New task force to address needs of cancer survivors
Cancer Therapy - 2-Methoxyestradiol immobilizes the growth of metastatic melanoma
Cancer Therapy - Assay predicts breast cancer response to tamoxifen and chemotherapy
Cancer Therapy - Company expands oncology pipeline with product candidates from the NCI, PHS
Cancer Therapy - Company files IND application for anticancer compound XL880
Cancer Therapy - New NIH research initiated on mushrooms to treat cancer
Cancer Therapy - New cancer compound licensed for development
Cancer Therapy - New treatment guidelines for reducing death from childhood cancers published
Cancer Therapy - Photocrosslinkable chitosan useful for endoscopic cancer therapy
Cancer Therapy - Researchers report findings on functions, benefits of cancer support groups
Cancer Therapy - Researchers report on role of isothiocyanates in cancer prevention
Cancer Therapy - Small molecule CDC25 phosphatase inhibitors synthesized
Cancer Therapy - Study results support epigallocatechin gallate as prooxidant
Cancer Therapy - Study to gauge use of Ecstasy drug by terminal cancer patients
Cancer Therapy - Toxicity and pharmacokinetics of NK911 elucidated
Cancer Vaccine - Dendritic cells fused with human cancer cells described
Cancer Vaccine - Methods to improve rituximab efficacy reviewed
Cancer Vaccine - Phase I study for antitumor CEA-TRICOM published
Cancer Vaccine - Tumor antigens and implications for cancer diagnosis and treatment reviewed
Candidemia - Candidemia is rare in allogeneic stem cell transplantation recipients
Cervical Cancer - Older women less likely to receive most aggressive treatments
Cervical Cancer - Type-specific associations of HPV load with cancer risk needs more study
Chondroma - Researchers report on case of chondroma in the external auditory canal
Chronic Myelogenous Leukemia - Tyrphostin AG1024 may be basis of novel therapy for STI571 refractory CML
Clinical Trials - Cirrhosis heightens metastasis risk in murine model
Collaborations - Alliance with Molecular Profiling Institute to introduce breast cancer test
Colon Cancer - Findings support role of genistein in colon tumor prevention, growth reduction
Colon Cancer Risk Factor - Tumor necrosis factor or insulin affects sulfotransferase activity in colon
Colon Cancer Screening - DNA test for colon cancer disappoints
Colorectal Cancer - Dendritic cells may play an important role in controlling local tumor immunity
Complementary & Alternative Medicine - Antioxidants may not help fight cancer
Complementary & Alternative Medicine - Doctors say herbal blend can help cancer patients
Complementary & Alternative Medicine - Lozenges may offer bite-sized cancer prevention!
Complementary and Alternative Medicine - Yale doctors say herbal blend can help cancer patients
Dendritic Cells - Immortalized dendritic cell line with cross-priming ability developed
Depression - Study shows importance of psychological assessments during cancer treatments
Dermatology - Lymphangiogenesis assays predict the progression of cutaneous melanoma
Developmental Biology - "Atlas" of key brain genes could speed research on cancer, neurological diseases
Digital Glomus Tumors - Digital glomus tumors excised through lateral subperiosteal approach
Drug Development - EviMed company announces new diagnostics for sepsis and acute renal failure
Drug Development - Novel estrogen-platinum(II) hybrid molecules evaluated vs. gynecologic cancers
Drug Development - Novel taxoids potent enough for targeted delivery via antibodies
Drug Development - Pharmaceutical company responds to MHRA action, affirms safety of Efexor drugs
Drug Development - Pharmaceutical company submits IND for cancer drug, makes board appointment
Drug Development - Zoledronic acid prevents bone loss in hormone-treated breast cancer patients
End-Of-Life Care - Interviews with proxies address end-of-life care preferences in older patients
End-of-Life Care - U.S. FDA okays Ecstasy study in cancer patients
Endocrinology - Roles of activin and inhibin in the human breast studied
Endometrial Cancer - API-59CJ-OMe may possess therapeutic potential for some endometrial cancers
Epidemiology - Researchers collect data on Arizona town's leukemia
Epithelioid Hemangioendothelioma - Researchers report on epithelioid hemangioendothelioma of the suprasellar area
Finance - Biopharmaceutical company files shelf registration statement
Finance - Biotech company announces proceeds of private placement
Finance - Cancer-focused drug development company adopts Shareholders' Rights Plan
Finance - Cancer-focused pharma company announces sale of 15M shares of common stock
Finance - Cell Therapeutics inks TRISENOX financing agreement
Finance - Immunotherapy company announces $53.7M private placement of common stock
Finance - Japanese therapeutics company raises $11.3 million in series C financing
Fitness and Wellness - Forget garden work, think garden exercise
Funding - Pharmaceutical company awarded SBIR grant from the National Cancer Institute
Gastric Cancer - IL-1B promoter variants possibly linked with increased gastric cancer risk
Gastric Cancer - Inactivating mutations of Siah-1 may be factor in gastric cancer development
Gastric Cancer - Researchers report on association of H. pylori and gastric cancer
Genetic Testing - Informed consent assessment requires appreciation of patient's risk, motivation
Genomics & Genetics - Mechanisms of E-cadherin silencing in SS elucidated
Gynecologic Cancers - Cytokeratin 7 and EMA help differentiate ovarian yolk sac tumors
HIV/AIDS Caregivers - Pschosocial differences identified between AIDS and cancer family caregivers
HIV/AIDS Therapy - Triple-drug therapy promising against African HIV subtype
HIV/AIDS-Associated Infection - Widespread and invasive Trichophyton rubrum infection mimics KS in AIDS patient
HIV/AIDS-Related Infection - Intramedullary tuberculoma mimicked primary CNS lymphoma in AIDS patient
Head and Neck Cancer - Advexin cancer therapy receives additional protection with issuance of patent
Head and Neck Cancer - Bioscience company reports positive EGF-R antibody pivotal phase 2 results
Head and Neck Cancer - New clinical data for Advexin shows promise
Hepatocellular Carcinoma - Researchers address key issues in hepatocellular carcinoma management
Hodgkin Disease - Consolidation chemotherapy for relapsed/refractory Hodgkin disease feasible
Information Technology - Health groups, publishers go online to give patients access to research
Information Technology - Healthcare marketing, communications company launches oncology-focused agency
Information Technology - New software aids in breast ultrasound
Injury Prevention - Coroner warns of snow-shoveling danger
Kaposi Sarcoma-Associated Herpesvirus - Cell replication/origin licensing factors required for KSHV latent replication
Kaposi Sarcoma-Associated Herpesvirus - KSHV+ solid lymphomas belong to spectrum of primary effusion lymphomas
Legal Issues - Cancer drug patent sparks Indian legal battle
Legal Issues - Tobacco farmers' group files notice to appeal judge's decision
Leukemia - Candidosis reported earlier with ELISA-based detection
Leukemia - Dacogen data presented at ASH meeting
Leukemia - Encouraging data reported from phase II trial of leukemia vaccine
Licensing - Agreement inked for small-molecule MHC class II antagonists program
Liver Cancer Risk Factor - Disruption of insulin signaling in diabetes may contribute to liver cancer
Lung Cancer - Encouraging survival rates push XYOTAX trial data release to end of Q1 2005
Lymphoma - Recombinant diabody and thalidomide combine to treat cancer in murine models
Mammography - Workup of patients with positive screening for breast cancer could be improved
Materials - New instruments at ORNL reactor will lead to dramatic increase in users
Medical Devices - Medical device company receives IDE for use of embolic device in trial
Medical Imaging - Company releases image package for early detection of breast cancer
Medical Reporting - Year in medicine report from Harvard Medical School focuses on medical advances
Melanoma - Clearance granted to commence trials of autologous cell vaccine
Melanoma - Protocol for phase I (b) study of Tubercin completed
Melanoma - Psoralen derivatives and longwave UV irradiation active against melanoma cells
Melanoma - Scientist discover the cellular roots of graying hair
Metastasis - Squamous cell carcinoma cells in suspension escape anoikis by aggregating
Multiple Myeloma - Paraneoplastic vasculitis can be associated with multiple myeloma
Multiple Myeloma - Proliferative activity of plasma cells shows prognostic value in MM patients
Multiple Myeloma - Results of 2 clinical trials of T cells in multiple myeloma presented
Myopathy - Class of myopathies is produced by abnormal desmin
Neutropenia - Data confirms activity of myeloid progenitor cells in chemo-induced neutropenia
Non-Small Cell Lung Cancer - Biopharmaceutical company comments on trial for cancer cell-activated drug trial
Oncogenesis - Microarray analysis distinguishes the molecular events of prostate cancer
Oncology - DNA chips to become 'identity cards' for cancer tumors
Oncology - Highly selective adenoviruses show specificity for melanoma cells
Oncology - Novel microtubule-associated protein identified in mice
Oncology - Subcellullar localization of tumor-associated antigen 3H11Ag determined
Oral Mucositis - U.S. FDA approves Kepivance for oral mucositis in marrow-transplant patients
Otorhinolaryngology - Anesthesia for cervicofacial cancer surgery reviewed
Ovarian Cancer - FSH activates certain important enzymes in sterol biosynthesis pathways
Ovarian Cancer - FSHR overexpression activates oncogenic pathways in surface epithelial cells
Ovarian Cancer - Mechanism of Nodal's protective effects elucidated in vitro
Ovarian Cancer - Women's psychological response to screening results impacted by several factors
Pancreatic Cancer - Dendritic cell vaccine has antitumor effect against pancreatic cancer
Pancreatic Cancer - Phase 1/2 trial of metabolism-targeting drug for pancreatic cancer initiated
Pancreatic Cancer - Phase II study of RP101 for metastatic pancreatic cancer initiated
Patent - Drug development company issued patent for regulation of mismatch repair
Patient Education - Cancer treatment awareness campaign wins award
Pediatric Leukemia - Genzyme wins approval for childhood leukemia drug
Personnel - Biotechnology company appoints senior vice president of clinical development
Personnel - Hemophilia foundation board names new CEO
Personnel - Medical device company announces management changes
Personnel - Robert S. Tenerowicz named vice president by biopharmaceutical company
Personnel - Timothy J. Kinsella, MD, joins bioscience company's scientific advisory board
Prostate Cancer - Clinical studies commence in prostate cancer patients
Prostate Cancer - Combining hormones with radiation helps high-risk prostate patients
Prostate Cancer - Dye reversal microarrays used to identify cytogenetic abnormalities
Prostate Cancer - Effect of evidence-based education package evaluated in prostate cancer patients
Prostate Cancer - P2Y receptors, ERK1/2 and p38 pathways affect prostate cancer invasion
Prostate Cancer - Pharma company announced draft decision for National coverage of Abarelix
Prostate Cancer - Study addresses use of alternative therapies after localized prostate cancer
Prostrate Cancer - Findings support role of genes at 15q, 20q in prostate cancer brain metastases
Proteomics - Regulation of BCL2 protein expression in B cells clarified
Quality Assurance - Study investigates value of "center of excellence" designation
Radiotherapy - Researchers address issue of radiotherapy-induced nausea, vomiting management
Skin Cancer - Growth of common skin cancer blocked in gene-switch mice
Smallpox Vaccine - Protein and genome analysis company awarded grant to develop smallpox vaccine
Stem Cell Research - SC expression of AML1/ETO fusion protein induces myeloproliferative disorder
Tobacco Use - CEO of foundation dedicated to smoke-free world comments on secondhand smoke
Tobacco Use - California-based lung association web site puts on-screen smoking in true light
Tobacco Use - Use of Health Department smoking quit line is up
Tobacco Use - Woman spends last days filming TV ads warning about dangers of smoking
Tumor Suppression - Interrupted Rb-Raf-1 interactions halt tumor growth and angiogenesis
Tumor Suppression - Kruppel-like factor 6 becomes inactivated in hepatocellular carcinoma
Tumor Suppression - Staurosporine induces G2 /M arrest in primary effusion lymphoma cells
Urogynecology - Radical hysterectomy may exacerbate pre-existing abnormal urodynamics
Vaccine Research - Company to launch cancer-vaccine research sub: BN ImmunoTherapeutics
Vaccine Vector - Adenoviral vector vaccine process to overcome anergy to antigens described
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