Skin Cancer
Growth of common skin cancer blocked in gene-switch mice
Published in Cancer Weekly, January 18th, 2005
Dr. Andrzej Dlugosz and colleagues at the University of Michigan and the U.S. National Cancer Institute have examined the functions of the Hedgehog (Hh) signaling pathway in basal cell carcinoma, the most common form of cancer, and have uncovered a subset of tumor cells that are resistant to inhibition of the Hh pathway. This new finding has important implications for the treatment of this widespread disease.
Their report was published in the January 15, 2005, issue of Genes & Development.
Basal cell carcinoma (BCC) affects over 1,000,000 Americans each year and frequently arises on sun-exposed sites such as the face. Surgical removal of BCCs...
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Source: Cancer Weekly (2005-01-18)
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