Cancer Genetics

BRCA1 mutation prevalence in ovarian tumors is low in Norway

Published in Cancer Weekly, January 18th, 2005

A study from Norway reports a low prevalence of the BRCA1 mutation in ovarian tumors among women listed in a population-based cancer registry there and the general population.

The researchers also determined that CA 125 is not a sensitive tool for ovarian cancer screening.

T. Bjorge and colleagues, Norwegian Radium Hospital, Oslo, set out "to find the frequency of the most common BRCA1 mutations in women with ovarian tumors identified from a population-based cancer registry and in the general population, to estimate the relative risk of ovarian tumors among the mutation carriers, and to explore the value of using CA 125 as a prediagnostic...

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Source: Cancer Weekly (2005-01-18)

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