Biliary Tract Cancer

S-1 demonstrates antitumor activity in biliary tract cancer

Published in Cancer Weekly, January 18th, 2005

Researchers from Japan reported antitumor activity in a study of an oral fluoropyrimidine derivative, S-1, in patients with advanced biliary tract cancer.

H. Ueno and coauthors wrote, "The aim of this study was to investigate the efficacy and safety of an oral fluoropyrimidine derivative, S-1, in patients with advanced biliary tract cancer.

"Patients with pathologically confirmed advanced biliary tract cancer, a measurable lesion, and no history of radiotherapy or chemotherapy were enrolled. S-1 was administered orally (40 mg m(-2) b.i.d.) for 28 days, followed by a 14-day rest period."

The authors reported, "A pharmacokinetic...

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Source: Cancer Weekly (2005-01-18)

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