Ovarian Cancer

Cell lines analyzed using array-based comparative genomic hybridization

Published in Cancer Weekly, January 25th, 2005

Geneticists in England have analyzed ovarian cancer cell lines using array-comparative genomic hybridization.

They reported their findings in the Journal of Pathology.

Maryou B.K. Lambros, of the Molecular and Population Genetics Laboratory at Cancer Research UK, London, and colleagues wrote, "In this study, 23 ovarian cancer cell lines were screened using array-comparative genomic hybridization (aCGH) based on large-insert clones at about 1 Mb density from throughout the genome."

The technique revealed, "The most frequent recurrent changes at the level of the chromosome arm were loss of chromosome 4 or 4q, loss of 18q, and...

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Source: Cancer Weekly (2005-01-25)

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